"While we sleep, skin cells dramatically ramp up their DNA repair, protein production and cell division" - this is how an overview article in Nature the nocturnal high-performance phase of the epidermis.
The myth is confirmed: Skin ageing is not only determined by creams, but also by the clock in our heads. Recent chronobiology studies show that more than 3,000 repair genes are activated in the keratinocytes between two and four o'clock in the morning. DNA repair enzymes and collagen synthesis are most active during precisely this time window - a "rush hour" that was clearly documented by the University of Manchester in 2024 on over 160 skin biopsies.
What happens when we sleep?
The internal clock shifts the cell cycle into repair mode instead of defensive mode; UV-induced mutations are "ironed out".
The stress hormone cortisol drops and inflammation markers fall.
Melatonin, usually known as the sleep hormone, acts as a powerful antioxidant and moisturizing booster in the dermis. A mouse study with 28 days of sleep restriction showed that external melatonin almost completely restored the damaged skin barrier.
The most modern sleeping pitfalls
Blue screen light is the most prominent circadian killer: it suppresses melatonin secretion in the evening, shifts the skin clock and increases free radicals that break down collagen. According to recent gene expression analyses, shift work or chronic "social jet lag" even halves the epidermis' nightly repair capacity.
Three practical hacks for a glow in the morning
Light diet - Dim screens or switch on blue light filters at least one hour before going to bed.
Delivering building blocks - Collagen peptides or essential amino acids in the evening give the body the material it needs at night.
Using circadian helpers - According to pilot studies, low-dose melatonin or CBD supplements improve sleep quality and thus nocturnal DNA repair.
The Natura Vitalis Night Routine
CBD Soft Gums relax and harmonize the body's own melatonin curve.
The Collagen Lift Drink supplies peptides plus vitamin C precisely when the fibroblasts incorporate collagen.
Die liposomale ProBioSkin∑® uses the increased microcirculation to channel active ingredients deep into the basal cell layer.
Conclusion: If you get your screen hygiene under control, take in the right micronutrients in the evening and support your circadian skin biology, you can turn every night into a free "overnight spa". Or, as dermatologist Prof. Steven Shuster puts it:
"Sleep is the most beneficial anti-ageing cure. All you have to do is not sabotage it."